The throwback date, considered a highlight of the schedule since it was introduced five years ago, was announced by the team as part of a series a game-by-game themes.
Included is the previously announced Nov. 11 Monday night game against the Miami Dolphins, when Hall of Fame defensive tackle Warren Sapp will be added to the Ring of Honor.
Also, teams will don pink accents on uniforms to show support for breast cancer for the Oct. 13 game against the Philadelphia Eagles. Among the day's activities will be a 5-kilometer run-walk fundraiser outside the stadium on the morning of the game. Details will be announced in the coming weeks.
The home finale against the San Francisco 49ers will feature a postgame concert as part of the team's second annual "Faith and Football" festivities.
The Bucs also announced that single-game tickets for all home games will go on sale at 10 a.m. July 17.
Tickets for the Sept. 15 regular-season home opener against the Saints are already available for purchase.
Individual tickets will be available in a pre-sale beginning at 10 a.m. Monday to season pass members.
The Bucs are 1-3 in throwback games, including last season's 35-28 loss to the New Orleans Saints.
In the 2009 throwback debut, quarterback Josh Freeman made his first start in a 38-28 victory over the Green Bay Packers. The Bucs lost to Atlanta in 2010 and Carolina in 2011 in the other throwback games.
The Bucs wore the Creamsicle-colored jerseys, with the winking-pirate helmet logo known as Bucco Bruce, from 1976 to 1996 before moving to their current pewter and red motif.